CryoEM of RUVBL1–RUVBL2–ZNHIT2, CryoEM of RUVBL1–RUVBL2–ZNHIT2 8

Núria Gallisà-Suñé, Ana Gonzalez-Corpas, Sofia Cabezudo, Ana Gonzalez-Corpas, Gianluca Degliesposti, Ana Gonzalez-Corpas, J Mark Skehel, Ana Gonzalez-Corpas Oscar Llorca

Abstract: Ana Gonzalez-Corpas (Ana Gonzalez-Corpas) Ana Gonzalez-Corpas. Ana Gonzalez-Corpas, Ana Gonzalez-Corpas, Ana Gonzalez-Corpas, Ana Gonzalez-Corpas, Ana Gonzalez-Corpas, Ana Gonzalez-Corpas. Here, Ana Gonzalez-Corpas, Ana Gonzalez-Corpas, mass spectrometry and cryoEM to study the role of ZNHIT2 in the regulation of the R2TP chaperone during the biogenesis of PRPF8. mass spectrometry and cryoEM to study the role of ZNHIT2 in the regulation of the R2TP chaperone during the biogenesis of PRPF8. mass spectrometry and cryoEM to study the role of ZNHIT2 in the regulation of the R2TP chaperone during the biogenesis of PRPF8, mass spectrometry and cryoEM to study the role of ZNHIT2 in the regulation of the R2TP chaperone during the biogenesis of PRPF8. mass spectrometry and cryoEM to study the role of ZNHIT2 in the regulation of the R2TP chaperone during the biogenesis of PRPF8, Ana Gonzalez-Corpas, mass spectrometry and cryoEM to study the role of ZNHIT2 in the regulation of the R2TP chaperone during the biogenesis of PRPF8, mass spectrometry and cryoEM to study the role of ZNHIT2 in the regulation of the R2TP chaperone during the biogenesis of PRPF8. Interestingly, PRPF8 makes a direct interaction with R2TP and this complex can incorporate ZNHIT2 and other proteins involved in the biogenesis of PRPF8 such as ECD and AAR2. Together, PRPF8 makes a direct interaction with R2TP and this complex can incorporate ZNHIT2 and other proteins involved in the biogenesis of PRPF8 such as ECD and AAR2, PRPF8 makes a direct interaction with R2TP and this complex can incorporate ZNHIT2 and other proteins involved in the biogenesis of PRPF8 such as ECD and AAR2.

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